Preliminary Scientific Program
Web version latest update: 2021-09-22 | PDF version latest update: 2021-09-22
10:45 | Registration
11:45 | Opening Ceremony
12:00 | Lucia Lisa Petrilli (Ospedale Pediatrico Bambino Gesù – IRCCS, Roma | Starting Grant 2020 Winner), Dissecting paediatric high grade-glioma through single-cell mass cytometry: from tissue to cell and back
12:15 | Lecture • Konstantinos Ampatzis, Locomotion dependent neuron-glia interactions control neurogenesis and regeneration in the adult spinal cord
12:45 | Lunch Box
18:35 | Poster session 1 + “Lost in the protocol” session
20:00 | Closing Remarks
13:00 | Registration
14:00 | Opening ceremony
14:15 | Marta Boccazzi (Starting Grant 2019 Winner), The immune-inflammatory response of oligodendrocytes in a murine model of preterm white matter injury: the role of TLR3 activation.
14:30 | Lecture • LUCAS SCHIRMER, Multilineage vulnerability and reactivity in chronic neuroinflammation.
SESSION 1 • NEUROINFLAMMATION, selected ORAL COMMUNICATIONS
15:00 – 15:15 – 15:30 | Accepted oral presentation (3)
15:45 | BraYn Educational Symposium 1
Andrea Paolillo (Merck Serono), Merck heritage and commitment in the new MS era: past, present and future.
16:05 | BraYn Educational Symposium 2
Francesca Sangalli (Sanofi), Innovation through patient needs: Bruton Tyrosine Kinase Inhibitor (BTKi) development journey.
16:25 | Coffee Break mini 1
17:00 – 17:15 – 17:30 | Accepted oral presentation (3)
18:00 | BraYn Educational Workshop 1
(Beckman Coulter), Technological enhancement in Flow cytometry.
18:15 | Poster session 1 (2h)
20:00 | Closing Remarks
Thomas C. Südhof (Nobel Laureate)
Department of Neuroscience, Karolinska Institutet (Sweden)
How do neurons react to changes? This is a central question of our research program. An intriguing feature of the nervous system is plasticity, the remarkable ability to change and adapt in light of internal and external stimuli. I work on different aspects of neuroplasticity since my undergraduate and postgraduate studies at the Biology Department of the University of Crete (Greece). After my PhD, I moved to UK (MRC clinical science centre- Imperial College of London) to perform my first postdoctoral training. Shortly after that, I moved to Sweden at Karolinska Institutet to conduct my postdoctoral training in motor systems. In 2016 I got my first position as an assistant professor at Karolinska Institutet to establish my lab.
Trinity College, Dublin (Ireland)
I’m a veterinarian and I have been working with laboratory animals since my PhD in zoonoses control (2010, University of Bologna). Afterwards I moved into Lab Animal Science, working with different species: mice, rats, fish (zebrafish and Nothobranchius furzerii), Xenopus, sheep, rabbits and cephalopods. I have managed animal facilities in Italy (CIBIO, University of Trento) and Czech Republic (FNUSA-ICRC, Brno). Currently, I’m the Facility Manager and Animal Care and Welfare Officer (ACWO) at Trinity College Dublin (Ireland). I’m a Board member of the European Society of Laboratory Animal Veterinarians (ESLAV).
Michelle Monje, MD, PhD, is an associate professor of Neurology and Neurological Sciences at Stanford University. Dr. Monje is recognized as an international leader in the pathophysiology of glioma, especially diffuse intrinsic pontine glioma (DIPG)/H3K27M-mutated diffuse midline gliomas and is a pioneer in the emerging field of Cancer Neuroscience. Her clinical focus is on childhood glial malignancies and cognitive impairment after childhood cancer therapy. Her laboratory studies neuron-glial interactions in health and disease, with a particular focus on mechanisms and consequences of neuron-glial interactions in health, glial dysfunction in cancer therapy-related cognitive impairment and neuron-glial interactions in malignant glioma. Together with these basic studies, her research program has advanced preclinical studies of novel therapeutics for pediatric high-grade gliomas and cancer therapy-related cognitive impairment in order to translate new therapies to the clinic. She has led several of her discoveries from basic molecular work to clinical trials for children and young adults with brain tumors.
Trinity College, Dublin (Ireland)
I obtained a master’s degree in Molecular Biology and a Phd in Cellular and Molecular Pathology and Biology. In 10 years of research activity at the University of Verona (Italy) I investigated the molecular mechanisms controlling leukocyte trafficking in the central nervous system during neuroinflammatory diseases such as experimental autoimmune encephalomyelitis, epilepsy and Alzheimer disease.
I also studied the immuno-modulatory properties of adipose-derived mesenchymal stem cells (ASCs) and ASC-derived nanovescicles in neurological diseases. I recently moved to the Trinity College Dublin (Ireland) to develop a research project investigating the metabolic regulation of adaptive immune responses.
San Raffaele Scientific Institute, Milan (Italy)
Barbara Bettegazzi, 35 years old, married. I am currently working as a post doctoral researcher in Professor Grohovaz’s laboratory at San Raffaele Scientific Institute in Milan, Italy, where I obtained my PhD in Molecular Medicine in 2012. During my PhD I worked mainly on Alzheimer’s disease pathogenesis, studying the mechanisms regulating the expression and activity of BACE1, the main β-secretase of the brain. During my PhD I spent two years in Munich, in the laboratory of C. Haass, a pioneer in the Alzheimer’s disease field and our collaboration is still ongoing. More recently I shifted my research focus on studying whether alterations in the control of protein synthesis could contribute to the development of complex diseases, like Alzheimer’s disease and epilepsy.
Neuroscience Institute «Cavalieri Ottolenghi», Dept. of Neuroscience, University of Turin (Italy)
Enrica Boda, 36 years old, married. Enrica is a neurobiologist sand has just got a position as Assistant Professor in tenure track (RTD-B) in Human Anatomy at the University of Turin. She’s now working in the research group of “Physiopathology of neural stem cells” at the Neuroscience Institute of the Cavalieri Ottolenghi Foundation (NICO, Orbassano, Turin). Her studies are focused on the molecular mechanisms regulating the self-renewal and differentiation of neural progenitor cells (oligodendrocyte progenitors andneural stem cells) in health and disease, with a special focus on de-/dis-myelinating diseases, such as Multiple Sclerosis and neurodevelopmental disorders.
University of Catania (Italy)
I’m Giovanna Calabrese, I have a PhD in Medical Embryology, Pathology and Experimental Hematology. Currently, I’m a post-doc at the University of Catania, Dept. of Biomedical and Biotechnological Sciences. My main research topic is regenerative medicine and tissue engineering applied to both neural and osteo/chondral regeneration. Specifically, I’m studying the repairing capabilities of the combination between mesenchymal stem cells and 3D biomimetic materials, both in vitroand in animal models.