Dear Young Neuroscientists,
The BraYn Association and the BraYn Conference team warmly welcome you to the 4th Brainstorming Research Assembly for Young Neuroscientists, the BraYn conference.
Inspired and organized by researchers under the age of 40 from different scientific backgrounds, the focus of the BraYn conference is to promote brand-new collaborative connections between the potential future leaders of Neuroscience. The conference philosophy is simple: to meet, to connect, to collaborate, and to share. We need to encourage cooperation between different research groups in order to broaden our horizons and to improve the quality of our research.
By hosting neuroscientists from all around the world, our goal is to make the BraYn conference a flagship event for young European researchers, where novel national and international research networks will be built to improve future research activities. This goal was fully achieved in past BraYn conferences, and we want to continue on this path in the future.
In addition to the traditional sessions on neurodegeneration, neuro-oncology, neuroinflammation, and neurophysiology & neural plasticity, this year we included two new sessions in the scientific program: neuroimaging and paediatric neuroscience & epilepsy. These sessions were added to meet the needs and the interests of researchers working in the clinical field.
Nearly 600 delegates attended the BraYn 2020 online conference. Unfortunately, because of ongoing restrictions related to the COVID-19 pandemic, it is not yet possible for us to fully and freely accept everyone registering for the BraYn conference. Nevertheless, we will continue to do our best to ensure that everyone who wishes to participate can do so.
We are looking forward to welcoming you at the 4th BraYn conference!
The BraYn Staff
Neuroimaging consists in using various techniques to image the structure, function, or physiology of the nervous system. It is subdivided into two main approaches: Structural imaging, which deals with the structure of the nervous system and the diagnosis of a large-scale intracranial disease (like tumors, multiple sclerosis lesions, stroke) and injuries (like traumatic brain injury); Functional imaging, which is used to diagnose metabolic diseases (like Alzheimer) and for neurological and cognitive psychology research as well as building brain-computer interfaces. The most commonly used techniques for neuroimaging are Computed tomography (CT), Diffuse optical imaging (DOI), Event-related optical signal (EROS), Magnetic resonance imaging (MRI), arterial spin labeling (ASL), Magnetoencephalography (MEG), electroencephalography (EEG), Positron emission tomography (PET), Single-photon emission computed tomography (SPECT) and cranial or functional ultrasound imaging. In this session, we will discuss the use of the mentioned techniques, both alone and in combination, to help in understanding and/or detecting various aspects of neurological diseases.
Neuroinflammation describes the inflammatory response initiated in the central nervous system (CNS) by resident cells or triggered by infiltrating immune cells. Furthermore, in neurodegenerative disease it is evident that neuroinflammation is a key player in central nervous system dysfunction. The neuroinflammation session is mainly devoted to basic and clinical research in multiple sclerosis (MS), Neuromyelitis Optica Spectrum Disorder (NMOSD) and other inflammatory disorders of the CNS which have a significant impact on the lives of young adults. Even though the scientific discoveries of recent decades have improved the therapeutic approach of those disease, there are still open questions. The aim of the present session will be to explore the pathogenic mechanisms, the role of immune system in the autoimmune response, the roles of genetics and environment in the development of neuroinflammatory disease and examine options within the patient-centered approach. This and other aspects will be debated in the present session.
Neurodegeneration is a key aspect of a large number of diseases characterized by progressive damage of the nervous system, which leads to irreversible neuronal death such as, but not limited to, Parkinson’s disease (PD) and Alzheimer’s disease (AD), tauopathies narcolepsy, depression and psychiatric disorders. PD is a slowly progressive syndrome that begins insidiously, gradually worsens in severity, and usually affects one side of the body before spreading to involve the other side. Rest tremor is often the first symptom recognized by the patient. But the illness sometimes begins with bradykinesia, and in some patients, tremor may never develop. AD is the most common type of dementia and it is an irreversible, neurodegenerative and progressive central nervous system disorder that slowly destroys memory and thinking skills, and, eventually, other mental abilities. During the BraYn conference we will be updated on the more recent advances in the field.
Neuro-oncology is an emerging field of investigation that studies nervous system tumors. As many of them can cause severe nervous system damage, neuro-oncology represents a trending research area in neuroscience, which may identify the molecular mechanisms involved in tumor pathogenesis. This would ultimately lead to the development of novel therapeutic approaches for the treatment of life-threatening diseases such as glioma, medulloblastoma. These topics will be discussed in depth during the session.
Paediatric neuroscience is a branch studying neurodevelopment and its disorders. The session will focus on biological mechanisms underlying developmental and epileptic encephalopathies, including genetic disorders and their management and treatment implications.