Welcome to the 2ND BraYn congress! The acronym BraYn stands for 'Brainstorming Research Assembly for Young Neuroscientists' and is a congress specifically aimed at young researchers under the age of 40 specialized in the field of Neuroscience. The main goal of this meeting is to encourage young researchers from different laboratories across Italy and Europe to meet, connect, collaborate and share in a space where they can exchange their knowledge and ideas, thereby establishing collaborations between groups

Scientific Program

Download The Preliminary scientific program HERE

Conference Days

  • Day 1 - 14 November 2019
  • Day 2 - 15 November 2019
  • Day 3 - 16 November 2019
  • Day 1 - 14 November 2019
    13:30 Registration
    14:30 Opening Ceremony
    14:40 Lecture
    Speaker : JEAN-MICHEL CIONI

    Axonal protein synthesis in health and disease: a new role for endosomes.

    15:10 Lecture
    Speaker : DANIEL JACQUE GARCIA

    Near infrared (NIR)-II imaging for brain studies.

    15:40-16:25 Session 1 - NEURAL PLASTICITY - Oral Communication
    15:40 : ROBERTA SCHELLINO

    Human medium spiny neuron progenitors grafted into an HD rat model early integrate into the host circuits, express striatal markers and support functional recovery.

    15:55 : MARTINA LORENZATI

    Axo-glial interplay in oligodendrocyte specification and myelination: role of JNK1.

    16:10 : GIULIA D'ARRIGO

    Astrocytes-derived Extracellular Vesicles in motion at the neuron surface.

    16:25-17:50 BraYn Educational Symposia 1
    16:25 : LUCA MAZZITELLI (Carlo Erba Reagents)

    Biology at true resolution with 10X Genomics.

    16:45 : FRANCESCA GALBIATI (Charles River Laboratories)

    Essential Tips for new Mouse Researchers.

    17:05-17:50 Session 1 - NEURAL PLASTICITY - Oral Communication
    17:05 : CRISTINA SPALLETTI

    Robotic Rehabilitation and neuromodulation after stroke: novel approaches in a mouse model.

    17:20 : VALENTINA CERRATO

    The ontogenesis of astrocytes diversity: a remarkably orderly process necessary for the correct cerebellar development and functioning.

    17:35 : MATTEO PEDRAZZOLI

    Glucocorticoid receptor modulation alters dendritic spine density and microglia activation in the hippocampus of 3xTg-AD mice.

    17:50-20:00 Poster Session 1 • Coffee break mini 1 BraYn Educational Workshop Session 1
    17:50 : STEFANO FIORINA (AB Sciex)

    Metabolomics & Lipidomics.

    18:40 : MARILISA MARINELLI, CLAUDIO COMUNIAN (Biorad)

    Extracellular Vesicles in Neurological Disease.

    19:15 : FRANCESCO BIANCARDI (Carl ZEISS)

    Beyond the Computed Tomography: X-Ray Microscopy in Life Science.

    20:00 Closing remarks
  • Day 2 - 15 November 2019
    09:00 Lecture
    Speaker : MARCO PRINZ

    Myeloid cell diversity in the central nervous system. (Chairwoman: R.C. Paolicelli)

    9:30-10:15 Session 2 - NEUROINFLAMMATION - Oral Communication
    9:30 : PLACIDO ILLIANO

    Astroglial TNFR2 regulates learning, memory and anxiety.

    9:45 : LAURA BRAMBILLA

    Real Time Quaking Induced Conversion assay as innovative tool to investigate neurodegeneration in Multiple Sclerosis.

    10:00 : ALESSANDRO LEUTI

    Resolution of inflammation is impaired in multiple sclerosis and entails a loss of pro-resolving features of monocytes/macrophages.

    10:15-12:00 BraYn Educational Symposia 2
    10:15 : ANGELA GUERRA ALVAREZ (Biogen)

    Pioneering the future of Neuroscience.

    10:35 : ZSOLT IVÁN (Femtonics)

    Outstanding benefits of breakthrough innovations of 3D Acousto-Optic technology in Neuroscience.

    10:50-11:35 Session 2 - NEUROINFLAMMATION - Oral Communication
    10:50 : VALENTINA SERPIERI

    Agenesis of the putamen and globus pallidus caused by recessive mutations in the homeobox gene GSX2.

    11:05 : MATTEO CARLO KALEVA CICCARESE

    Role of lipid mediators in the aging process.

    11:20 : MORRIS LOSURDO

    Preconditioned Bone Marrow Mesenchymal Stem Cell- derived Extracellular Vesicles Exert Immunomodulatory Effects in a model of Alzheimer’s Disease.

    11:35 Workshop
    Speaker : CHIARA GABBI

    How to write a succesful grant and/or a fellowship application (Chairwoman: M. Romeo)

    12:00 - 14:00 Lunch box with Poster Session 2 | BraYn Educational Workshop Session 2
    12:00 : ELISA ZUFFI (Miltenyi Biotec)

    Novel approach to study adult neural cells in vitro.

    13:00 : PIETRO VEGLIANESE (Beckman Coulter)

    Modulation of microglial cells by drug-nanovectors in spinal cord injury.

    13:30 : PAOLA MARCON (Biogen)

    The long journey: from the bench to the bedside.

    14:00 Lecture
    Speaker : ROSSELLA GALLI

    Leveraging brain tumor stem cells for disease modeling and therapy improvement. (Chairwoman: B. Bettegazzi)

    14:30-15:15 Session 3 - NEURO-ONCOLOGY - Oral Communication
    14:30 : MASSIMILIANO DEL BENE

    Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients.

    14:45 : PAOLA INFANTE

    Oncogenic role of the aminopeptidase ERAP1 in Hedgehog- dependent cancer.

    15:00 : SILVIA VALTORTA

    Combined Positron Emission Tomography imaging approach for identification of new potential biomarkers for treatment response in glioma models.

    15:15-15:30 BraYn Educational Symposium 3
    15:15 : PHILIPPE TROCHET (Fujifilm)

    See the Whole Mouse Brain in vivo and in Real-time.

    15:30-18:30 Session 3 - NEURO-ONCOLOGY - Oral Communication
    15:30 : PROSPERO CIVITA

    Towards a 3D all human in vitro model of glioblastoma multiforme for drug screening: glioblastoma and astrocyte interactions?

    15:45 : CARMELA SERPE

    Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma.

    16:00 : CARMELA SERPE

    Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma.

    15:45 : ELENA PARMIGIANI

    Notch signaling controls glioma proliferation and shapes the tumor microenvironment.

    16:00-18:30 Coffee break with poster session III with “Lost in the Protocol” session
    18:30 Lecture
    Speaker : PIERRE GRESSEN

    Neuroinflammation and encephalopathy of prematurity. (Chairman: L. Ramenghi).

    19:00-20:30 Session 4 - PERINATAL NEUROLOGY - Oral Communication (Supported by EuBrain)
    19:00 : ERIDAN ROCHA-FERREIRA

    Repurpose of exendin-4 for the treatment of neonatal brain injury.

    19:15 : SARA DE CRESCENZO

    Growth parameters and minor brain lesions in very low birth weight (VLBW) newborns as prognostic factors of negative neurodevelopmental outcome at two and three years of age.

    19:30 : CRISTIANA PELOROSSO

    A novel double-hit mechanism involving different genes of the MTOR pathway in hemimegalencephaly with intractable childhood epilepsy.

    20:30 BraYn Social dinner
  • Day 3 - 16 November 2019
    09:00 Lecture
    Speaker : SONIA GAREL

    Microglia at the crossroads of cortical wiring and environmental signals. (Chairwoman: R.C. Paolicelli)

    9:30-10:30 Session 5 - NEURODEGENERATION - Oral Communication
    9:30 : BIANCA BARZAGHINI

    Therapeutic effect of neural progenitor cells expanded in the 3D nano-engineered Nichoid substrate in a Parkinson’s disease preclinical model.

    9:45 : MORGAN ROUAULT

    Incorporation of spatial mapping and confirmation of gene signatures by a multiplex in situ hybridization technology into single cell RNA sequencing workflows.

    10:00 : FEDERICA CAMPANELLI

    Effects of chronic continuous theta-burst stimulation (cTBS) on bidirectional striatal synaptic plasticity in a model of Parkinson’s disease and L-Dopa- induced dyskinesia.

    10:15 : LOREDANA LEGGIO

    Astrocyte-derived extracellular vesicles and cell-to-cell communication in the nigrostriatal regions: implications for dopaminergic neuroprotection.

    10:30-12:10 BraYn Educational Symposia 4
    13:30 : GENNARO PAGANO (Roche)

    Translational medicine journey in neurodegeneration: focus on alpha-synuclein.

    13:30 : GIANLUCA ROTTA (BD Biosciences Italia)

    Three intersections between flow cytometry and multiple sclerosis.

    11:10-12:10 Session 5 - NEURODEGENERATION - Oral Communication
    11:10 : MARIA VELASCO-ESTEVEZ

    Mechanosensation: a new horizon in the regulation of myelination?

    11:25 : CRISTIANO CARLOMAGNO

    Raman spectroscopy as biochemical “fingerprint” of biofluids for the investigation of neurodegenerative diseases.

    11:40 : SILVIA PICCIOLINI

    SPRi-based biosensor for the detection of circulating extracellular vesicles as biomarkers of neurological diseases.

    11:55 : LUDOVICO CANTUTI-CASTELVETRI

    Defective cholesterol clearance limits remyelination in the aged central nervous system.

    12:10 Lecture
    Speaker : GIACOMO RIZZOLATTI

    The mirror mechanism: a neural mechanism for understanding others. (Chairman: G. Nardo)

    12:40 Closing remarks, BraYn awards (Best oral and poster presentation and BraYn small Starting Grant)

Invited Speakers

Rossella Galli

Sonia Garel IBENS ,Paris, France

Chiara Gabbi Humanitas Research Hospital, Italy

Pierre Gressens INSERM, Paris, France

Daniel Jaque Garcia Associate Professor Fluorescence Imaging Group @ Universidad Autónoma de Madrid (UAM), Madrid, Spagna.(FIG@UAM) Nanobiology Group

Marco Prinz University of Freiburg, Germany

Giacomo Rizzolatti University of Parma, Italy

Jean Michel Cioni San Raffaele Scientific Institute, Milan, Italy